Schizophr Bull 43:1045–1055Īrseneault L, Cannon M, Fisher HL, Polanczyk G, Moffitt TE, Caspi A (2011) Childhood trauma and children’s emerging psychotic symptoms: a genetically sensitive longitudinal cohort study. Schizophr Bull 38:661–671Ībajobir AA, Kisely S, Scott JG, Williams G, Clavarino A, Strathearn L, Najman JM (2017) Childhood maltreatment and young adulthood hallucinations, delusional experiences, and psychosis: a longitudinal study. Varese F, Smeets F, Drukker M, Lieverse R, Lataster T, Viechtbauer W, Read J, van Os J, Bentall RP (2012) Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective- and cross-sectional cohort studies. Van Dam DS, van der Ven E, Velthorst E, Selten JP, Morgan C, de Haan L (2012) Childhood bullying and the association with psychosis in non-clinical and clinical samples: a review and meta-analysis. The cumulative effect of being bullied from peers and experiencing other adversities during childhood and/or adolescence, together with genetic liability for psychosis, appears to confer the highest risk for developing psychotic symptoms later in life.
Lack of studies hampered the results about the age of trauma occurrence.
Meta psychotic full#
No significant meta-regression was found between the risk of developing a full clinical psychosis or a psychotic experience. Moderator analysis showed that negative effects of bullying were detected especially in those with genetic liability for psychosis and exposure to multiple trauma types studies with higher prevalence of males showed a stronger risk for those exposed to parental death. Bullying by peers (OR = 2.28 ), maltreatment by an adult (OR = 2.20 ) and parental death (OR = 1.24 ) all increased the risk of psychosis. Three sets of meta-analyses estimated the risk of developing psychotic experiences or full clinical psychosis by having experienced maltreatment by an adult or bullying by peers or parental death, using the random-effects model. Studies were identified by searching Embase-Ovid, PsycINFO (EBSCO), Pubmed, Scopus, Web of Science databases, and yielded an initial total of 9016 papers, leaving finally 23 after the screening process. The aim of the present meta-analysis was to explore the temporal relationship between the development of psychosis and traumatic exposure using prospective studies and to examine the role of moderation factors on overall effect sizes. Evidence of the association between traumatic experiences and psychosis are uncertain with respect to temporal order, clinical outcomes and the role of the age and genetic liability.